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Entitled, “Implementation of a Pharmacist-Led Pharmacogenomics Service for PACE (PHARM-GENOME-PACE)”, the article was published online
“It is well-known that individuals respond in different ways to the same medication or combinations of medications,” said
Pharmacists’ roles in the study were interpreting and applying PGx data, determining how to disseminate those data to prescribers, advocating for appropriate PGx testing in PACE, and educating prescribers about the application of test results to clinical practice.
A key finding of the study was PACE participants frequently were on medications posing drug-gene interactions (DGIs) risks, with the majority (73.6%) having >1 reported interaction. Importantly, the overwhelming majority (89.0%) of pharmacists’ recommendations to mitigate risks were accepted by referring physicians.
“The conclusion of the study is implementing a pharmacist-led PGx service for PACE is feasible,” said lead author,
“Analyzing and interpreting PGx testing results, and guiding clinical decisions based on such results, are vital services by pharmacists for the improvement of medication responses and patient outcomes. What this study demonstrates is the innovative practice of pharmacist-led PGx testing, interpreting and consulting,” stated Knowlton.
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